Thursday, December 29, 2011

Melasma/ Chloasma

Chloasma is a condition of hyperpigmentation of skin of face caused mainly by hormones or Ultraviolet rays exposure.
Chloasma often first appears during pregnancy or while the patient is taking oral contraceptive pills and this indicates an influence of female hormones.
Sunlight- Pigmentation becomes darker after sun exposure. So UV rays are important.
Age- Peak incidence age is 35-50 years.
Clinical Features- Brown pigmentation with well defined borders mainly over cheeks, nose, forehead and chin.

The pigmentation becomes darker on sun exposure.
Treatment:
1. Protection from Sunlight- Sunscreens, Minimum with SPF 15.
2. Topical Hydroquinone 2-4%
3. Topical Retinoic acid 0.025%
4. Topical Corticosteroids like Mometasone
5. Glycolic Acid (6-12%) at night
6. Azelaic acid (20%).

Chemical peeling- The agents used are-
1. Glycolic acid (70%)
2. Trichloroacetic acid (15-30%)